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53, 54 One study has indicated that eosinophils mediate this effect at least in part by release of the aforementioned prosurvival factors APRIL and IL-6, whereas another has proposed that eosinophil-derived IL-1 is responsible

Further clinical trials should be conducted evaluating the use of isolated polyphenols in IBD subjects, whereas the use of curcumin, resveratrol, or biphenol-rich nutraceuticals could also be considered or tested by clinicians due to their promising benefits [613,614], although many cautions should be taken, as to date it is difficult to find standardized protocols, formulas or recommendations regarding their use

Avoid smoking Stop smoking and vaping any substances for the week before and the following weeks

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