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Whether these findings pointed to a weight loss efficacy of PYY was evaluated in a 12-week trial of 133 obese patients who were randomly assigned to intranasal PYY3-36 (200 or 600 mcg three times a day before meals) or placebo, in conjunction with diet and exercise

The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life

Patients should be provided with a letter from their healthcare provider or pharmacy documenting the medical necessity of carrying injection supplies

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