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doi: 10.1038/nrneurol.2016.88 178

In the case of the former, and as it has been remarked throughout the whole manuscript, polyphenols partly exert their therapeutic action by modulating the gut microbiota

EMBO J (2000) 19(18):497685.10.1093/emboj/19.18.4976 2 LiuSCaiXWuJCongQChenXLiTet alPhosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

In another study, historic sera, which were able to neutralize 229E sequences from the time of collection, failed to neutralize strains isolated 817 years later