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In a recent 12-week, randomized, placebo-controlled trial in untreated hypertensive subjects, daily intake of aged garlic extract (1.2 g of which contained 1.2 mg of S-allyl-L-cysteine [SAC]) was shown to significantly lower SBP by 11 mm Hg and DBP by 6 mm Hg on average in 50%-60% of participants, but reductions in blood pressure were not reported in 40%-50% of participants compared to placebo (110)

Other studies that support a reduction in GSH levels in melasma subjects compared to controls are studies conducted by Jing et al 12 and also by Hamadi et al

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses