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In addition, impaired glymphatic or paravascular clearance in AD may alter the elimination of brain-delivered nanoparticles, potentially affecting retention, regional distribution, and long-term safety during repeated dosing ( 6 Opportunities, challenges, and future directions In recent years, nanoparticles have emerged as a promising strategy in AD therapy, offering considerable potential for precise drug delivery while presenting challenges that must be carefully addressed by researchers

Other genetic variants have been found to increase the risk of either adverse events or vaccine effectiveness and it makes more sense to study those genes in conjunction with vaccination reactions

doi: 10.1093/ije/dyv080 38

Available at: (Accessed: February 19, 2023)