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Laboratory assessment includes measurement of vitamin B 12 levels (methylmalonic acid with or without homocysteine can provide additional information) to evaluate for vitamin B 12 deficiency, particularly in patients receiving metformin 147 , thyroid function tests and serum immunoelectrophoresis with immunofixation to evaluate for a monoclonal gammopathy

The mechanisms of multiple components in Banxia Xiexin Decoction warrant further investigation, given its prominence as a traditional medicine for gastritis and the fact that berberine is derived from this decoction